Local vasoconstrictor for nasal decongestion
What is Otrivin used for?
Otrivin is used as a local vasoconstrictor for nasal decongestion. Its active substance, xylometazoline, is an arylalkyl imidazoline. Otrivin, which is intended for use in the nose, constricts the nasal blood vessels, thereby decongesting the mucosa of the nose and neighbouring regions of the pharynx. Otrivin thus makes it easier to breathe through the nose when suffering from a cold or chill.
The effect of Otrivin sets in within a few minutes and persists for up to 12 hours. Otrivin is well tolerated and it does not impair the function of the ciliated epithilium even when the the mucous membranes are sensitive. Otrivin is unlikely to cause reactive hyperaemia.
Otrivin is indicated for colds of various types, and to aid drainage of secretions in sinus conditions. In otitis media, Otrivin is an adjuvant to decongest the nasopharyngeal mucosa. Otrivin is also used to facilitate rhinoscopy.
Following the local application of Otrivin, the plasma concentration of the active substance is too low to be detected with current analytical method.